Acute Leukemia

Data on acute leukemia reported by researchers at University of Debrecen

Published in Medical Imaging Law Weekly, June 3rd, 2008

"The intracellular form of the coagulation factor XIII has previously been identified by immunomorphological techniques using polyclonal antibodies. In these studies, only the A subunit (FXIII-A) was detectable in megakaryocytes/platelets and in monocytes/ macrophages," investigators in Debrecen, Hungary report.

"We developed several novel monoclonal antibody clones directed to both subunits (FXIII-A and FXIII-B) and investigated their appearance in normal and leukemic cells. By using 3- and 4-color flow cytometry FXIII expression was investigated in normal peripheral blood and bone marrow samples and in acute myeloblastic (AML) and lymphoblastic (ALL) leukemia cases....

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Source: Medical Imaging Law Weekly (2008-06-03)

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