Proteomics

Research on proteomics described by E. Garciagarayoa and colleagues

Published in Medical Imaging Law Weekly, January 27th, 2009

According to recent research published in the European Journal of Nuclear Medicine and Molecular Imaging, " Neurotensin (NT) and its high affinity receptor (NTR1) are involved in several neoplastic processes. Thus, NT-based radiopharmaceuticals are potential tracers for targeted diagnosis and therapy of NTR-positive tumours."

"A new analogue based on NT(8-13), NT-XIX, with the three enzymatic cleavage sites stabilised, was synthesised and tested. The synthesis was performed by Boc strategy. Labelling with Tc-99m/Re-188 was performed using the tricarbonyl technique. Metabolic stability was tested in vitro and in vivo. NT-XIX was further characterised in vitro in...

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Source: Medical Imaging Law Weekly (2009-01-27)

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