Experimental Model

Investigators at University of Sao Paulo target experimental model

Published in Medical Imaging Law Weekly, April 14th, 2009

According to recent research from Sao Paulo, Brazil, "We assessed a new experimental model of isolated right ventricular (RV) failure, achieved by means of intramyocardial injection of ethanol. RV dysfunction was induced in 13 mongrel dogs via multiple injections of 96% ethanol (total dose 1 mL/kg), all over the inlet and trabecular RV free walls."

"Hemodynamic and metabolic parameters were evaluated at baseline, after ethanol injection, and on the 14th postoperative day (POD). Echocardiographic parameters were evaluated at baseline, on the sixth POD, and on the 13th POD. The animals were then euthanized for histopathological analysis of the hearts. There was a 15.4%...

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Source: Medical Imaging Law Weekly (2009-04-14)

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