Friedrich Schiller University Hospital
Near-infrared imaging detects HER-2 overexpression by tumor cells
Published in Medical Imaging Week, July 10th, 2004
Radiologists in Germany conducted a study "to evaluate in vitro and in vivo imaging of HER-2-overexpressing tumors using near-infrared optical imaging."
"A fluorochrome probe was designed by coupling Cy5.5 to anti-HER-2 antibodies," explained I. Hilger and coauthors working at Friedrich Schiller University Hospital in Jena. "Cells overexpressing (SK-BR-3 cells) or normally expressing (PE/CA-PJ34 cells) the HER-2 protein were incubated with the probe. After removing unbound probe molecules, fluorescence intensities were determined (a.u.: arbitrary...
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Source: Medical Imaging Week (2004-07-10)
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