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Netherlands Institute for Developmental Biology

Research in toxicology provides new insights

Published in Medical Imaging Week, February 5th, 2005

Reports from Netherlands and South Korea highlight recent research on toxicology.

Study 1: In utero images of estrogen receptors depict bisphenol A activity.

"Environmental estrogens are of particular concern when exposure occurs during embryonic development. Although there are good models to study estrogenic activity of chemicals in adult animals, developmental exposure is much more difficult to test. The weak estrogenic activity of the environmental estrogen bisphenol A (BPA) in embryos is controversial," researchers in the Netherlands report.

"We have recently generated transgenic mice that carry a reporter construct with...

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