Published in Medical Imaging Week, December 10th, 2005
"Structural brain volume abnormalties are among the most extensively studied endophenotypes in schizophrenia. Bivariate genetic model-fitting (adjusted to account for selection) was used to quantify the genetic relationship between schizophrenia and brain volumes and to estimate the heritability of these volumes."
"We demonstrated by simulation that the adjusted genetic model produced unbiased estimates for endophenotype heritability and the genetic and environmental correlations," wrote F.V. Rijsdijk and colleagues of the Institute of Psychiatry in...
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