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Federal University of Sao Paulo

Administration of dexrazoxane during treatment with doxorubicin resulted in less cardiotoxicity

Published in Medical Imaging Week, December 31st, 2005

Scientists found that administration of dexrazoxane during treatment with doxorubicin resulted in less cardiotoxicity.

In a recent article published in the journal Pediatric Blood & Cancer, scientists in Brazil detailed a study conducted "to assess the late cardioprotective effect of dexrazoxane associated with doxorubicin during treatment of osteosarcoma by means of low-dose dobutamine stress echocardiography (LDDSE) in non-relapsed asymptomatic children and teenagers."

"The study population included 58 patients with osteosarcoma divided in three groups, with equivalent age range, gender proportion and body surface area. Group I (21 patients,...

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