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Aging

Reports from Wilmer Eye Institute add new data to research in aging

Published in Medical Imaging Week, November 25th, 2006

Scientists discuss in "Aging changes of mouse corneal endothelium and Descemet's membrane" new findings in aging. According to a study from the United States, "The purpose of this study was to characterize age-associated changes in the corneal endothelium and Descemet's membrane (DM) in C57BL/6 mice, an inbred strain commonly used as a genetic disease model. Corneas from mice aged 2 weeks to 24 months were studied."

"Light microscopy was used to assess central endothelial cell density, area, and morphology. Transmission electron microscopy was used to assess thickness and ultrastructural features of DM. Central corneal endothelial cell density showed a rapid decline...

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