Life Sciences
New life sciences data have been reported by researchers at University of Maryland, Department of Pharmaceutical Sciences
Published in Medical Imaging Week, January 20th, 2007
Researchers detail in "Transport of poly(amidoamine) dendrimers across Caco-2 cell monolayers: Influence of size, charge and fluorescent labeling," new data in life sciences. In this recent study, researchers in the United States conducted a study "To investigate the transport of poly(amidoamine) (PAMAM) dendrimers with positive, neutral and negatively charged surface groups across Caco-2 cell monolayers. Cationic PAMAM-NH2 (G2 and G4), neutral PAMAM-OH (G2), and anionic PAMAM-COOH (G1.5-G3.5) dendrimers were conjugated to fluorescein isothiocyanate (FITC)."
"The permeability of fluorescently labeled PAMAM dendrimers was measured in the apical-to-basolateral direction....
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Source: Medical Imaging Week (2007-01-20)
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