Published in Medical Imaging Week, November 8th, 2008
"We hypothesized that increasing plasma ET-1 concentration during hypoxia would enhance HPV in humans and might represent a strategy for improving gas exchange during single-lung anaesthesia or respiratory disease. Nine healthy volunteers were each exposed twice to a 7-h protocol consisting of 1 h breathing air, 4 h of eucapnic hypoxia (end-tidal Po-2, 50 mm Hg), and 2 h of eucapnic euoxia (end-tidal Po-2, 100 mm Hg). Volunteers received a...
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