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Bioluminescence

New bioluminescence research from A. Kondo and colleagues discussed

Published in Medical Imaging Week, May 30th, 2009

According to recent research published in the journal Childs Nervous System, "Currently, there is no conclusive treatment for brainstem tumor. To facilitate the development of new treatments, it is essential to establish predictive preclinical in vivo models in which therapeutic modalities can be evaluated."

"Although a few rodent models have been reported, there is no novel approach that can monitor tumor response qualitatively and quantitatively. Bioluminescence imaging was used to characterize a rat brainstem tumor model. In this model, 9L gliosarcoma cells, transduced with an onco-retroviral vector containing the luciferase coding sequence, were inoculated...

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