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Diagnostics (HCV)

"Cloning and Sequencing of the NS3, NS4, and NS5 Regions of Hepatitis C Virus from a Russian Case of Chronic Hepatitis."

Published in Medical Letter on the CDC and FDA, January 29th, 1996

According to an abstract presented by the authors to the 1st International Conference on Therapies for Viral Hepatitis, held December 11-15, 1995, in Kauai, Hawaii, "Background: A number of hepatitis C virus (HCV) strains from different geographic areas have been isolated and subject to genomic sequence analysis. As the number of HCV isolates analyzed increases, the heterogeneity of HCV genotypes has become apparent. Objectives: Few HCV sequence data are available from the Former Soviet Union. To investigate the genomic characterization of a HCV Russian isolate (HCVR) we have cloned and sequenced the HCV genome spanning the nonstructural domain NS3, NS4, and NS5 and...

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