Therapy (Halofantrine)
Standard-Dose Is Associated with Lengthening the QT Interval
Published in Medical Letter on the CDC and FDA, May 13th, 1996
Because halofantrine hydrochloride has been associated with cardiac arrhythmias, Paul A. Matson, North Carolina Department of Environment, Health and Natural Resources, Raleigh, North Carolina, and colleagues investigated the potential for the standard dosage of the drug to cause cardiac arrhythmias ("Cardiac Effects of Standard-Dose Halofantrine Therapy," American Journal of Tropical Medicine & Hygiene, 1996;54(3):229-231). Also involved in this effort were researchers from the U.S. Centers for Disease Control and Prevention (CDC), Atlanta, Georgia.
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