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Lyme Disease (Diagnostics)

OspA and OspB Bands May Need to be Reconsidered

Published in Medical Letter on the CDC and FDA, June 10th, 1996

The exclusion of certain bands from new Lyme disease diagnostic criteria may result in underdiagnosis.

In October 1994, the Second National Conference on the Serologic Diagnosis of Lyme Disease (Centers for Disease Control and Prevention/Association of State and Public Health Laboratory Directors [CDC/ASTPHLD]) recommended new criteria for serological testing and interpretation of Western blots (immunoblots) in the diagnosis of Lyme disease (CDC, MMWR, 1995;44:590-591).

Eileen Hilton and colleagues, Long Island Jewish Medical Center, New Hyde Park, New York, reviewed the recommendations and reported on their evaluation of how the new criteria...

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