Diagnostics (TB)
"Use of pTBN12 as a Secondary DNA Fingerprinting Probe for Epidemiologic Studies of Tuberculosis in a Large Geographic Area."
Published in Medical Letter on the CDC and FDA, July 15th, 1996
According to an abstract submitted by the authors to the 96th General Meeting of the American Society for Microbiology, held May 19-23, 1996, in New Orleans, Louisiana, "IS6110-based DNA fingerprinting of Mycobacterium tuberculosis (Mtb) is being used globally to study the epidemiology of TB in many populations. We previously reported that when IS6110 is used alone as a probe in population-based fingerprinting studies, patients who are grouped into clusters based upon common IS6110 fingerprints frequently can not be linked epidemiologically. This is especially true when the isolates contain <6 copies of IS6110. The purpose of this study was to...
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