Epidemiology (Polio)
"Molecular Analysis of Wild Type 1 Poliovirus Isolated From Patients and Sewage Samples Collected In Israel, Gaza, and the West Bank Reveals at Least Three Independent Introductions of the Virus into This Region. DOUBLEQUO
Published in Medical Letter on the CDC and FDA, February 10th, 1997
According to an abstract submitted by the authors to the 10th International Congress of Virology, held August 11-16, 1996, in Jerusalem, Israel, "Molecular epidemiological methods and environmental sampling assume greater importance for monitoring wild poliovirus as the global effort to eradicate poliomyelitis approaches its goal. Surveillance of AfP cases and contacts is the traditional method for determining presence of wild poliovirus. New methods must be developed to confirm elimination of subclinical infections as AFP approaches background levels. Sewage sampling with RT-PCR sequence analysis of virus isolates combine rapid, highly sensitive molecular epidemiology with detection of...
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