Pathogenesis (Malaria)
"Role of Malarial Antigen-Induced Immune Stimulation on HIV-1 Replication."
Published in Medical Letter on the CDC and FDA, February 24th, 1997
According to an abstract submitted by the authors to the 45th Annual Meeting of the American Society of Tropical Medicine and Hygiene, held December 1-5, 1996, in Baltimore, Maryland, "The time for the progression from initial HIV infection to AIDS in malaria-endemic areas is significantly shorter than in non-malarious regions. However, the effect malaria has on HIV infection and replication has not been evaluated. Although malaria infection-stimulated production of proinflammatory cytokines may be protective against malaria parasites, this immune stimulation may have deleterious effects on HIV replication. Therefore, we investigated the effect of malaria antigens on in vitro infection...
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