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Nosocomial Infections

 Enterococcus faecalis Genome Sequenced

Published in Medical Letter on the CDC and FDA, May 19th, 1997

Human Genome Sciences, Inc. (HGS), Rockville, Maryland, announced that it has determined the genomic sequence of the bacterium Enterococcus faecalis.

This organism, a normal part of the intestinal flora, is emerging as a major component of hospital-caused acquired infections. Infections caused by E. faecalis include urinary tract, surgical wound, abdominal, pelvic, and neonatal infections. E. faecalis is an important cause of endocarditis and mortality due to enterococcal bacteremia.

It is estimated that well over 800,000 cases per year of enterococcus infections are reported in the U.S. alone, the third largest cause of...

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