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Occupational Risk

Management Of Significant Occupational Exposures To Hepatitis C Virus

Published in Medical Letter on the CDC and FDA, August 11th, 1997

The latest U.S. Centers for Disease Control and Prevention guidelines regarding occupational exposure to hepatitis C virus (HCV) recommend against post-exposure prophylaxis with antiviral agents such as alpha interferon or with immunoglobulin.

They do recommend, however, that health care workers who sustain percutaneous or permucosal exposures to anti-HCV positive blood should be followed up actively. This includes immediate testing of the source patient for anti-HCV and, if positive, testing the exposed person at the time of injury for anti-HCV and after six months for anti-HCV and alanine amino transferase activity.

Guidance on the management of...

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