Ethical Issues (HIV/AIDS)

Controversial Part of AIDS Trials Dropped

Published in Medical Letter on the CDC and FDA, November 10th, 1997

U.S. researchers said they had decided to drop segments of AIDS trials in Africa in which subjects received only placebos and no drugs, but denied they were doing so in response to recent criticism.

The trials were designed to see whether drug treatments could stop pregnant women from passing on HIV to their babies. More than 830,000 children around the world are infected with HIV and most got it from their mothers.

The trials have been criticized because some of the women get placebo instead of AZT. Placebo arms are important to scientific trials because they provide a baseline measurement.

Groups like Public Citizen, founded...

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Source: Medical Letter on the CDC and FDA (1997-11-10)

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