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Testing (TB)

PPD Skin Testing Valuable in BCG Vaccinated Populations

Published in Medical Letter on the CDC and FDA, November 24th, 1997

Tuberculin skin testing can identify active Mycobacterium tuberculosis infection in children who have received prior bacillus Calmette-Guerin vaccination, according to a report from the U.S. Centers for Disease Control and Prevention (CDC) and the Botswana Ministry of Health.

In a study of tuberculosis infection among children in Botswana, where 90 percent of infants receive bacillus Calmette-Guerin (BCG) vaccination at birth, researcher D. Rumisha and colleagues found that an induration of 10 mm was indicative of active infection and not vaccine-induced anergy.

The authors also found a surprisingly high incidence of tuberculosis infection...

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