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Drug Resistance (TB)

"Outbreak of Drug-Resistant Tuberculosis with Second-Generation Transmission in a High School California."

Published in Medical Letter on the CDC and FDA, February 9th, 1998

According to the authors' abstract of an article published in Journal of Pediatrics, "Background: In spring 1993, four students in a high school were diagnosed with tuberculosis resistant to isoniazid, streptomycin, and ethionamide. Methods: To investigate potential transmission of drug-resistant tuberculosis, a retrospective cohort study with case investigation and screening by tuberculin skin tests and symptom checks was conducted in a high school of approximately 1400 students. Current and graduated high-school students were included in the investigation, DNA fingerprinting of available isolates was performed. Results: Eighteen students with active...

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