Vaccination (TB)

Second BCG Course Unnecessary in Nonendemic Areas

Published in Medical Letter on the CDC and FDA, May 18th, 1998

The efficacy of revaccinating against tuberculosis with bacillus Calmette-Guerin is extremely low in countries not endemic for tuberculosis, according to a report from Finland.

"Revaccinating tuberculin-negative children has no scientific basis," Marianna M. Tala-Heikkila and colleagues wrote ("Bacillus Calmette-Guerin Revaccination Questionable with Low Tuberculosis Incidence," American Journal of Respiratory and Critical Care Medicine, April 1998;157:1324-1327).

"It has even been suspected that children with weak tuberculin sensitivity may be at risk of reactivation from focal reactions after BCG vaccination."

The...

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Source: Medical Letter on the CDC and FDA (1998-05-18)

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