HBV Vaccines
"Hepatitis B Virus DNA in Persons With Isolated Antibody to Hepatitis B Core Antigen Who Subsequently Received Hepatitis B Vaccine."
Published in Medical Letter on the CDC and FDA, May 25th, 1998
According to the authors' abstract of an article published in Clinical Infectious Diseases, "Serum samples from 133 persons who were positive only for antibody to hepatitis B core antigen (anti-HBc) by enzyme immunoassay (EIA) were re-tested for seromarkers of hepatitis B virus (HBV) by radioimmunoassay and for HBV DNA by polymerase chain reaction analysis. All persons were subsequently vaccinated with hepatitis B vaccine. HBV DNA was found in only five persons, four of whom remained positive during retesting. Most persons had a primary antibody response with three doses of hepatitis B vaccine. Evidence of HBV DNA was not detected in 96% of persons with isolated anti-HBc by EIA." The...
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