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Conference Coverage (1st Annual Vaccine Research)

The Ethics of Making People Sick

Published in Medical Letter on the CDC and FDA, June 29th, 1998

Is it ever ethical to deliberately infect a person with a disease'

Yes, says University of Maryland researcher Carol O. Tacket. Tacket's job is to test candidate vaccines by giving paid volunteers - both vaccine and placebo recipients - infectious doses of pathogenic organisms.

"Challenge models have in some cases expedited the development of potentially effective vaccines and, in others, led to the rejection of ineffective vaccines," she said.

Tacket spoke in an invited presentation to the First Annual Conference on Vaccine Research, held May 30-June 1, 1998, in Washington, D.C.

Robert Chen, chief of vaccine...

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