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Hepatitis E Virus

"Primary Structure of Open Reading Frame 2 and 3 of the Hepatitis E Virus Isolated from Morocco."

Published in Medical Letter on the CDC and FDA, February 15th, 1999

According to the authors' abstract of an article published in Journal of Medical Virology, "The nucleotide sequence from position 5,014 to 7,186 of the hepatitis E virus (HEV) genome was determined using a set of 10 polymerase chain reaction (PCR) fragments amplified directly from a pool of fecal specimens obtained from patients with well-documented epidemic HEV infection in Morocco. This sequence contains the 3'-terminal region of open reading frame 1 (ORF1), full length ORF2 and ORF3, and a portion of the 3'-noncoding region. The HEV Morocco nucleotide sequence was compared with the corresponding sequences of 13 HEV strains. A region of ORF2 that overlaps with ORF3 was found to be the...

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