Conference Coverage (Retrovirus)

Around the World, Natural Resistance To PIs

Published in Medical Letter on the CDC and FDA, March 15th, 1999

All over the world there are naturally occurring HIV strains resistant to a major part of the AIDS drug arsenal, according to a U.S. Centers for Disease Control and Prevention (CDC) report.

The drugs, HIV protease inhibitors, initiated the new era of highly active antiretroviral therapy (HAART) when it was found that in combination with nucleoside reverse transcriptase inhibitors they could reduce virus to undetectable levels. Despite their expense, the requirement that they be taken at the proper times each and every day, and their often difficult-to-manage side effects, this class of drugs remains a mainstay of AIDS therapy.

But now it seems that...

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Source: Medical Letter on the CDC and FDA (1999-03-15)

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