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Cancer Vaccines

"Tumor Vaccines Containing Reconstituted Tumor Membranes."

Published in Medical Letter on the CDC and FDA, April 12th, 1999

NIH Grant Number: IR55CA72474-01A1. Grant Expires: September 14, 1999. Principle Investigator: Peter E. Jensen. Performing Organization: Emory University, Atlanta, Georgia. Description: Considerable effort has recently been focused on increasing the immunogenicity of tumors by using gene transfer techniques with the goal of developing useful cellular vaccines for treatment of Cancer. Promising results have been obtained in experimental models in which tumors are engineered to express genes encoding cytokines, costimulatory molecules such as B7, or MHC proteins. However, a number of technical problems may limit the practical utilization of...

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