Diagnosis

PCR Testing of Aspirates Doesn't Spot TB in Children

Published in Medical Letter on the CDC and FDA, April 12th, 1999

The U.S. Centers for Disease Control and Prevention's (CDC's) standardized case definition for tuberculosis may be too restrictive for the routine identification of pediatric TB.

Researchers from New York's Columbia University suggest that the difficulty identifying tuberculosis in children may lead to erroneous diagnoses.

Natalie Neu and colleagues found that polymerase chain reaction testing had only limited use in diagnosing tuberculosis in the gastric aspirates of children, but that computed technology scanning was useful.

"Our findings in this small sample would suggest that the CDC clinical case definition should be modified...

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Source: Medical Letter on the CDC and FDA (1999-04-12)

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