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Opportunistic Infections

"Risk for Primary Pneumocystis carinii Pneumonia After the CD4+ T Lymphocyte Count Rises Above 200 Cells/MICROSYMBOLL."

Published in Medical Letter on the CDC and FDA, April 19th, 1999

According to an abstract submitted by the authors to the 36th Annual Meeting of the Infectious Diseases Society of America, held November 12-15, 1998, in Denver, Colorado, "The risk for PCP after antiretroviral therapy (ART) has produced a rise in the CD4 count from <200 to above this threshold (CD4 bump) remains unclear. To examine this issue, we analyzed data from ASD, a national longitudinal medical record surveillance study, and compared patients with a CD4 bump to patients who had not been observed to have a CD4 count <200. Group I (n=1,685) had a CD4 count <200 cells/(mu)L which was followed by a >100 CD4 cell rise to >200 cells/(mu)L associated with prescription of...

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