Published in Medical Letter on the CDC and FDA, April 19th, 1999
The correct early diagnosis of Lyme disease, a tick-associated spirochetal illness, is important because antibiotic therapy is effective. Prompt, appropriate treatment can prevent serious musculoskeletal, cardiac, dermatologic, and neurologic manifestations of long-term infection.
Serology plays a valuable role in the correct diagnosis of Lyme disease. Currently the most commonly used serologic tests use whole-cell antigens of Borrelia burgdorferi, the spirochetal agent of Lyme disease.
The 37-kDa...
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