"Genetic Analysis of a Case Involving Pre-Seroconversion Transmissions from HIV Contaminated Blood Products."

According to an abstract submitted by the authors to the Keystone Symposia HIV Vaccine Development: Opportunities and Challenges and AIDS Pathogenesis, held January 7-13, 1999, in Keystone, Colorado, "The role of host and viral factors in HIV sequence evolution and transmission has been previously studied in cohorts of patients infected from a common source, such as hemophilia transfusions. We have studied an HIV contaminated transfusion cohort which included a plasma donor who donated before seroconversion, one adult recipient of his red blood cells, and one child recipient of his platelets. The donor's plasma specimen was negative for HIV by the most commonly used assays (antibody,...

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