Leishmaniasis
Immunostimulatory DNA Sequences Expert Systemic Effects
Published in Medical Letter on the CDC and FDA, July 26th, 1999
Resistance to murine leishmaniasis correlates with development of a CD4+ T helper 1 (Th1)-predominant immune response.
Patricia S. Walker, National Institutes of Health, Bethesda, Maryland, and colleagues performed a study to determine whether immunostimulatory CpG-containing oligodeoxynucleotides (CpG-ODN), known to promote a Th1 immune response, could provide protection from Leishmania infection ("Immunostimulatory Oligodeoxynucleotides Promote Protective Immunity and Provide Systemic...
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