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Transmission (Vertical)

Affordable, Effective Drug Regimen for Infants of Mothers with HIV

Published in Medical Letter on the CDC and FDA, August 9th, 1999

A joint Uganda-U.S. study has found a highly effective and safe drug regimen for preventing transmission of HIV from an infected mother to her newborn that is more affordable and practical than any other examined to date.

Interim results from the study, sponsored by the U.S. National Institute of Allergy and Infectious Diseases (NIAID), demonstrate that a single oral dose of the antiretroviral drug nevirapine (NVP) given to an HIV infected woman in labor and another to her baby within three days of birth reduces the transmission rate by half compared to a similar short-course of AZT.

If implemented widely in developing countries, this intervention...

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