Published in Medical Letter on the CDC and FDA, August 9th, 1999
No easy and reliable methods allowing for the quantification of B. burgdorferi in tissues of infected humans or animals currently are available, noted Andreas Pahl and colleagues of Germany's University of Erlangen-Nurnberg.
Because of the lack of suitable assays to detect B. burgdorferi CFU and the qualitative nature of the currently performed polymerase chain reaction (PCR) assays, Pahl et al. decided to exploit the recently developed real-time PCR ("Quantitative Detection of Borrelia burgdorferi by Real-Time...
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