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Malaria

Cellular Responses to P. falciparum Major Surface Antigens

Published in Medical Letter on the CDC and FDA, August 9th, 1999

Recent findings highlight the influence of risk factors associated with different activities and immune responses to malaria antigens.

In Brazil, two types of activities have led to the worsening of malarial transmission in the Amazon region: prospecting/mining and agricultural settlements.

L.H. Carvalho and colleagues analyzed the cellular response of 52 of these individuals (14 gold-miners and 38 farmers) living within the same endemic area ("Cellular Responses to Plasmodium falciparum Major Surface Antigens and Their Relationship to Human Activities Associated with Malaria Transmission," Am J Trop Med Hyg, 1999;60(4):674-9).

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