Blood Banking (Disease Associations)

Association between Storage Duration and Postoperative Pneumonia

Published in Medical Letter on the CDC and FDA, August 23rd, 1999

There may be an association between the length of storage of transfused red cells and the development of postoperative pneumonia.

"We relate for the first time the postoperative infection rate in perioperatively transfused patients to the length of storage of the RBC [red cells] components received," wrote E.C. Vamvakas and J.H. Carven ("Transfusion and Postoperative Pneumonia in Coronary Artery Bypass Graft Surgery: Effect of the Length of Storage of Transfused Red Cells," Transfusion, 1999;39:701-710).

The researchers also compared postoperative infection rates in transfused and untransfused patients, after adjusting for effects of known...

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Source: Medical Letter on the CDC and FDA (1999-08-23)

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