AIDS Therapies

Researchers Identify Liver Toxicity Risk of AIDS Drugs

Published in Medical Letter on the CDC and FDA, January 17th, 2000

Ten percent of HIV infected individuals taking antiretroviral drugs experience liver toxicity at a level high enough to warrant stopping treatment, according to new findings by Johns Hopkins University researchers.

Results of the study, published in the January 5, 2000, issue of the Journal of the American Medical Association (JAMA), also showed that liver toxicity was five times higher with taking one particular protease inhibitor, ritonavir, which accounted for half of all cases in the study.

"Based on anecdotal reports, there had been a feeling that all protease inhibitors were equally toxic to the liver and that is not what we found," says...

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Source: Medical Letter on the CDC and FDA (2000-01-17)

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