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Type 2 Diabetes

Genetic Link Identified in Pima Indians

Published in Medical Letter on the CDC and FDA, July 2nd, 2000

A recent study of over 1,300 Pima Indian DNA samples identified areas on three chromosomes that may be linked to type 2 diabetes.

Clifton Bogardus and colleagues with the U.S. National Institute of Diabetes and Digestive and Kidney Diseases in Phoenix, Arizona, scanned the DNA samples' microsatellite markers to locate the genes that are responsible for type 2 diabetes development among Pima Indians.

In a sib-pair assessment, regions on chromosomes 1 and 7 were identified as possibly being related to diabetes and an area on chromosome 11 was linked to both diabetes and obesity, they reported.

"The genetic linkage to diabetes on...

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