Coagulation

FDA Approves Easier-to-Administer Heart Clot-Dissolving Drug

Published in Medical Letter on the CDC and FDA, July 2nd, 2000

A new clot-busting drug approved by the U.S. Food and Drug Administration (FDA) can reduce the time it takes to treat heart attack victims from 90 minutes to five seconds, using a single swift injection to dissolve clots that choke off the heart's blood supply.

Tenecteplase, made by Genentech Inc., won FDA approval on June 2, 2000, and will be made widely available as soon as possible to treat the nation's biggest killer, company officials said.

Genentech also makes TPA under the brand name Activase, currently the standard medicine for treating heart clots. Both of the drugs dissolve blockages in a similar fashion, preventing further permanent...

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Source: Medical Letter on the CDC and FDA (2000-07-02)

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