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Vaccine Safety

Study Evaluates Risk of Acute Flaccid Paralyses in Brazil

Published in Medical Letter on the CDC and FDA, November 5th, 2000

Oral poliovirus vaccine (OPV) has been related to acute flaccid paralyses in Brazil.

"At the present time, in Brazil and other countries in the Americas, the only cases of paralytic poliomyelitis due to poliovirus are caused by vaccine strains," wrote L.H. Deoliveira and colleagues, Rio de Janeiro. "The recognition of possible determinants of vaccine-associated paralytic poliomyelitis (VAPP) by public health surveillance and immunization programmes is relevant to inform the debate on criteria for case definition and vaccination strategies."

Deoliveira et al. published their study in the International Journal of Epidemiology...

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