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Tuberculosis

Short-Course Rifampin and Pyrazinamide Is Effective For Prison Inmates

Published in Medical Letter on the CDC and FDA, April 1st, 2001

A short-course of rifampin and pyrazinamide treatment for tuberculosis was well tolerated and increased the number of jail inmates completing therapy, researchers at the U.S. Centers for Disease Control and Prevention report.

Jail inmates, who constitute a known reservoir of latent tuberculosis infection, could benefit from treatment but are often released before they can complete the traditional six-month isoniazid regimen, N.N. Bock and associates said. The researchers tested a two-month short-course of rifampin and pyrazinamide (2RZ) and found that about half of the inmates that started treatment were able to complete the regimen.

Their...

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