Tuberculosis
TB Protein Reactivates Waning Immunity Of Current Vaccine
Published in Medical Letter on the CDC and FDA, April 29th, 2001
They reported their findings in the April 2001 issue of the journal Infection and Immunity.
"For several decades the Mycobacterium-bovis-derived bacillus Calmette-Guerin (BCG) has been the only widely used vaccine for tuberculosis and accumulating data from clinical trials and subsequent meta-analysis have tended to reveal its general ineffectiveness in adults," said J.V. Brooks and colleagues. "The mechanism underlying the gradual loss of effectiveness of BCG as the individual...
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