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West Nile Fever

Yale Researchers Develop First Vaccine, Test In Animal Model

Published in Medical Letter on the CDC and FDA, November 18th, 2001

Yale scientists have successfully immunized mice against West Nile virus, raising the possibility of developing a vaccine for humans against the potentially fatal, mosquito-borne infection.

Although there have been about 10 virus-related deaths reported to date in the United States, West Nile virus is considered an emerging disease, according to Erol Fikrig, MD, associate professor of medicine and in the Department of Epidemiology and Public Health at Yale School of Medicine, who directed the study.

"Its seriousness as a public health threat is not fully known yet," he said. "That should become apparent over the next two to three years. If the...

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