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Study shows promising use of proteomics and bioinformatics in ovarian cancer detection

Published in Medical Letter on the CDC and FDA, March 17th, 2002

Results of a study published in the The Lancet show that a new method of assessing protein patterns in blood samples was able to detect 100% of ovarian cancer cases, even at the elusive early stage when the cancer is most survivable.

In an analysis of 116 blinded blood samples - 50 from patients with cancer and 66 with nonmalignant disease - the researchers were able to correctly identify all 50 cases of ovarian cancer, including, most significantly, all 18 stage I cases. Of the controls, 63 of the 66 (95%) were identified as noncancer. This is a vast improvement over the currently used ovarian cancer detection technique of identifying the tumor marker CA125...

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