Weight Loss

Drug targets brain circuits that drive appetite and body weight

Published in Medical Letter on the CDC and FDA, September 29th, 2002

Research conducted in animals has revealed that an appetite suppressant drug, D-fenfluramine (D-FEN), activates brain pathways that regulate food intake and body weight. The NIH-funded study suggests that drugs targeting central nervous system pathways affecting appetite, obesity, and anorexia may lead to selective, effective treatments for weight control.

Results appear in the journal Science (2002;297(5581):609-611).

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found that anorexia induced by d-FEN in rodents activates melanocortin neurons in the central nervous system. The drug, once prescribed for losing...

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Source: Medical Letter on the CDC and FDA (2002-09-29)

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