Adverse Drug Events

Acetaminophen overdose chief cause of liver failure

Published in Medical Letter on the CDC and FDA, January 19th, 2003

Unintentional acetaminophen overdose is the most common cause of acute liver failure in the United States, research from the University of Texas (UT) Southwestern Medical Center at Dallas shows.

"This study is the first to prospectively characterize a large number of patients with acute liver failure," said Dr. William M. Lee, professor of internal medicine at UT Southwestern and the study's principal investigator. "Until recently, only limited data have been available on the causes and outcomes of acute liver failure because of its rarity and a lack of centralized data registry."

The scientists' findings appear in the December 2002 issue of the...

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Source: Medical Letter on the CDC and FDA (2003-01-19)

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