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Vaccine Efficacy

Varicella vaccine fails to protect against infection

Published in Medical Letter on the CDC and FDA, February 2nd, 2003

An outbreak of varicella occurred at a daycare center despite high vaccination coverage of the children attending the center.

"In seven studies of the effectiveness of the varicella vaccine conducted since it was licensed, the effectiveness was 71-100% against disease of any severity and 95- 100% against moderate and severe disease," reported Karin Galil and colleagues at the United States Centers for Disease Control and Prevention, the New Hampshire Department of Health and Human Services, and Washington State University. "We investigated an outbreak of varicella in a population of children with a high proportion of vaccinees who were attending a day-care center in a...

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