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Smallpox

Researchers recount lessons learned from Boston smallpox epidemic

Published in Medical Letter on the CDC and FDA, February 23rd, 2003

The manifestations of smallpox during an epidemic that occurred in Boston in 1901 have been recounted by a group of researchers from the United States.

"Clinical records of 243 patients with smallpox consecutively admitted to the Southampton Street smallpox hospital in Boston, Massachusetts, during the 1901-1903 epidemic were reviewed," reported Michael R. Albert and colleagues at the National Institutes of Health, the National Cancer Institute, and Yale-New Haven Hospital.

They continued, "Smallpox was divided into five categories of varying severity; 47% of patients had varioloid, a relatively mild form of the disease usually occurring in...

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