Influenza Virus
Influenza virus matrix protein plus ribonucleoproteins may control viral growth
Published in Medical Letter on the CDC and FDA, February 23rd, 2003
According to a study from the United States, "The matrix protein (M1) of influenza virus plays a central role in viral replication. In relation to viral growth and morphology, we studied the RNP-binding activity of M1s from high-growth strain A/Puerto Rico/8/34 (A/PR8/34) and the relatively low-growth wild-type strain A/Nanchang/933/95. The RNP-binding strength of M1 was studied by disruption of M1 from M1/RNP complexes with salt and acidic condition."
"Our results indicated that binding of M1 of high-growth A/PR8/34 was more difficult to break than the binding of M1 of low-growth A/Nanchang/933/95," reported Teresa Liu and colleagues at the Food and Drug...
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